USES OF AZATEND O 300MG TABLET

• Management of acute myeloid leukaemia (blood cancer) in adults

HOW AZATEND O 300MG TABLET WORKS

AZATEND O 300MG TABLET is an anticancer medication. It works by blocking the actions of certain enzymes (DNA/RNA methyltransferase) within the tumour cells that are required for the cells to grow and multiply. It also reduces the production of new genetic material (RNA and DNA) within the cells. As a result, it prevents abnormal cell division within the body, slows down the growth of tumour cells, and helps the bone marrow produce normal blood cells.

DIRECTIONS FOR USE

Take AZATEND O 300MG TABLET as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. AZATEND O 300MG TABLET can be taken with or without food.

Your doctor will decide the correct dose and duration of therapy for you depending on your age, body weight, and disease condition. Do not stop taking this medicine without consulting your doctor.

SIDE EFFECTS OF AZATEND O 300MG TABLET

COMMON

• Constipation, stomach pain
• Infections of the nose, sinuses and throat
• Lung infection (pneumonia)
• Tiredness, weakness
• Loss of appetite
• Generalized pain (sharp or dull) affecting different parts of the body
• Stiff joints, back pain
• Flu
• Urinary tract infection
• Hay fever
• Anxiety
• Weight loss

Stop taking AZATEND O 300MG TABLET and inform your doctor immediately if you experience any of the following side effects:

• Increased bleeding or bruising due to a low blood platelet count
• Severe infections with fever due to low WBC count in blood
• Severe diarrhoea, vomiting or nausea

HOW TO MANAGE SIDE EFFECTS

Constipation

Try to eat more high-fibre foods such as fresh fruit, vegetables, cereals, and drink plenty of water. Try doing exercise regularly (going for a daily walk or run). If this does not help, inform your doctor for receiving alternate treatments for constipation.

WARNING & PRECAUTIONS

PREGNANCY

CONTRAINDICATED

AZATEND O 300MG TABLET is not recommended for use in pregnant women as it may harm the growing baby. Therefore, consult your doctor before taking it. Women of childbearing potential must use a suitable contraceptive to avoid pregnancy while undergoing therapy with AZATEND O 300MG TABLET and until 6 months after stopping the therapy. If you accidentally became pregnant while receiving AZATEND O 300MG TABLET, inform your doctor immediately.

BREASTFEEDING

CONTRAINDICATED

AZATEND O 300MG TABLET is not recommended for use in breastfeeding women. Therefore, consult your doctor before taking it.

DRIVING AND USING MACHINES

USE WITH CAUTION

AZATEND O 300MG TABLET may cause tiredness, weakness and problems in concentration. Therefore, do not drive or operate any machines if your ability is affected by AZATEND O 300MG TABLET.

ALCOHOL

CONSULT YOUR DOCTOR

Avoid consumption of alcohol while taking AZATEND O 300MG TABLET as it may make you feel drowsier.

LIVER

USE WITH CAUTION

AZATEND O 300MG TABLET should be used with caution in patients with liver problems. Therefore, consult your doctor before taking it.

USE IN PEDIATRICS

CONTRAINDICATED

AZATEND O 300MG TABLET is not recommended for use in children and adolescents (aged below 18 years) due to lack of safety data. Therefore, consult your doctor for advice before taking it.

USE IN GERIATRICS

USE WITH CAUTION

AZATEND O 300MG TABLET should be used with caution in elderly patients (aged 65 years or above). Therefore, consult your doctor before taking it.